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Physiology Research

Physiology Research

Dr. Adel Pezeshki

Dr. Pezeshki’s research focuses on nutritional biochemistry of proteins and amino acids. In particular, he is interested in understanding the effect of individual amino acids and dietary proteins on health and growth development of young pigs and the physiological mechanisms by which they regulate energy balance and nutrients digestion, absorption and metabolism at cellular and whole-body levels. Further, he is interested in understanding the effect of other nutritional factors on proteins/amino acids digestion and absorption in the gut and their metabolism in various organs. Using young pigs for his research, the ultimate goal of Dr. Pezeshki’s research program is to develop novel strategies to improve the metabolic health and growth during postnatal life. Dr. Pezeshki’s group approaches the above aims by assessing various physiological parameters and mechanisms using variety of technologies and tools. Dr. Pezeshki’s dual purpose research contributes to swine and pediatrics nutrition and hence it benefits both agricultural and health care industries.

Dr. Leon Spicer

Dr. Spicer’s research endeavors involve a wide range of in vivo and in vitro approaches to study nutritional and hormonal control of ovarian function and follicular development.  Experimental approaches span from evaluating control of steroidogenesis, mitogenesis and gene expression in ovarian cells to determining the effect of nutritional supplements on ovarian function and milk production in dairy cattle.

Dr. Spicer’s recent efforts have utilized microarray technology to discover genes involved in the control of ovarian function.  Specifically, his laboratory has discovered several unique porcine granulosa cell genes stimulated by insulin-like growth factor 1, including thrombospondin and fibroblast growth factor 2 receptor.  In addition, bovine granulosa cell gene expression in cystic and normal follicles were compared and several novel genes not previously identified in bovine follicles were discovered, including Indian hedgehog protein, brain ribonuclease, and fibroblast growth factor 9 (FGF9).  This work has led to identification of possible roles for Indian hedgehog protein, brain ribonuclease, and FGF9 in ovarian follicular development in cattle.

Faculty

Dr. Adel PezeshkiAdel Pezeshki
Assistant Professor
Nutritional Physiology
206C Animal Science
405.744.8852
Email
Linkedin Google Scholar Research Gate

 

Leon SpicerLeon Spicer
Professor
Reproductive Physiology
114D Animal Science
405.744.9268
Email

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