You are here: Home / Research / Research Disciplines / Physiology Research

Physiology Research

Physiology Research

Dr. Adel Pezeshki

Dr. Pezeshki’s research focuses on nutritional biochemistry of proteins and amino acids. In particular, he is interested in understanding the effect of individual amino acids and dietary proteins on energy balance and metabolism, identifying key molecules that regulate these changes and characterizing the pathways for their action. Pezeshki’s group approaches the above aims by assessing various physiological parameters and mechanisms using variety of technologies and tools. Further, Pezeshki’s lab is interested in investigating the effect of environmental and genetics factors or interaction of both on proteins/amino acids digestion and absorption in the gut and their metabolism at cellular and whole-body levels. The ultimate goal of Pezeshki’s dual purpose research is to develop novel strategies to improve the metabolic health and growth in both animals and humans and hence it benefits both agricultural and health care industries.

Dr. Leon Spicer

Dr. Spicer’s research endeavors involve a wide range of in vivo and in vitro approaches to study nutritional and hormonal control of ovarian function and follicular development.  Experimental approaches span from evaluating control of steroidogenesis, mitogenesis and gene expression in ovarian cells to determining the effect of nutritional supplements on ovarian function and milk production in dairy cattle.

Dr. Spicer’s recent efforts have utilized microarray technology to discover genes involved in the control of ovarian function.  Specifically, his laboratory has discovered several unique porcine granulosa cell genes stimulated by insulin-like growth factor 1, including thrombospondin and fibroblast growth factor 2 receptor.  In addition, bovine granulosa cell gene expression in cystic and normal follicles were compared and several novel genes not previously identified in bovine follicles were discovered, including Indian hedgehog protein, brain ribonuclease, and fibroblast growth factor 9 (FGF9).  This work has led to identification of possible roles for Indian hedgehog protein, brain ribonuclease, and FGF9 in ovarian follicular development in cattle.

Faculty

Dr. Adel PezeshkiAdel Pezeshki
Assistant Professor
Nutritional Physiology
206C Animal Science
405.744.8852
Email
Linkedin Google Scholar Research Gate

 

Leon SpicerLeon Spicer
Professor
Reproductive Physiology
114D Animal Science
405.744.9268
Email

Linkedin Google Scholar PubMed Research Gate

 

Facilities

In the Media

Other Links

It's a Brand, It's a Tradition, It's You